Directions
Address the following in a paper no longer than two double-spaced pages (not including the reference page) and in APA format. Include at least three peer-reviewed, evidence-based references.
1. Explain the differences between the four main actions a drug can have after binding to a receptor. Describe what an agonist, partial agonist, antagonist, and inverse agonist are. List one or two psychiatric medications that are an example of each of these categories.
2. What is a G-protein-linked receptor? What is an ion channel? How do these differ from each other? Give an example of a neurotransmitter and a medication that act on a G-protein receptor and ion channel.
3. Explain how this information influences how you prescribe medications. Give an example of a patient case or scenario where understanding the drug’s action at the receptor would be critically important in safely treating the patient.
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Rubric
G-Protein-Linked Receptors
| G-Protein-Linked Receptors |
| Criteria |
Ratings |
Pts |
| This criterion is linked to a Learning OutcomeAgonist-to-Antagonist Spectrum and Medications |
| 10.0 to >8.0 pts
All information is accurate and shows a deep understanding of the spectrum. Includes 2 medications in each category. |
8.0 to >6.0 pts
Most information is accurate and shows a strong understanding of the spectrum. Includes 1 or 2 medications in each category. |
6.0 to >4.0 pts
Some information is accurate and shows a basic understanding of the spectrum. Includes 1 or 2 medications in each category. |
4.0 to >2.0 pts
Most information is inaccurate and shows little understanding of the spectrum. Includes 0-1 medications in each category. |
2.0 to >0 pts
Information is inaccurate and shows no effort in understanding the spectrum. Does not includes medications in each category. |
|
10.0 pts |
| This criterion is linked to a Learning OutcomeReceptor Superfamilies |
| 10.0 to >8.0 pts
All information is accurate and shows a deep understanding of the receptor superfamilies. |
8.0 to >6.0 pts
Most information is accurate and shows a strong understanding the receptor superfamilies. |
6.0 to >4.0 pts
Some information is accurate and shows a basic understanding of the receptor superfamilies. |
4.0 to >2.0 pts
Most information is inaccurate and shows little understanding the receptor superfamilies. |
2.0 to >0 pts
Information is inaccurate and shows no effort in understanding the receptor superfamilies. |
|
10.0 pts |
| This criterion is linked to a Learning OutcomeImpact |
| 10.0 to >8.0 pts
All information is accurate and shows a deep understanding of the impact on prescribing. Includes a well-written, appropriate example. |
8.0 to >6.0 pts
Most information is accurate and shows a strong understanding of the impact on prescribing. Includes an appropriate example. |
6.0 to >4.0 pts
Some information is accurate and shows a basic understanding of the impact on prescribing. Includes a poorly written or not fully appropriate example. |
4.0 to >2.0 pts
Most information is inaccurate and shows little understanding of the impact on prescribing. Does not include an appropriate example. |
2.0 to >0 pts
Information is inaccurate and shows no effort in understanding the impact on prescribing. Does not include an appropriate example. |
|
10.0 pts |
| This criterion is linked to a Learning OutcomeWriting, Composition, Grammar, Spelling, References, and APA Format |
| 10.0 to >8.0 pts
Excellently written and composed. No errors in format, references, spelling, and grammar. |
8.0 to >6.0 pts
Well written and composed. A few minor errors in format, references, spelling, and/or grammar. |
6.0 to >4.0 pts
Somewhat well written and composed. Many minor errors in format, references, spelling, and/or grammar. |
4.0 to >2.0 pts
Poorly written and composed. Major errors in format, references, spelling, and/or grammar, but still understandable. |
2.0 to >0 pts
Very poorly written and composed. Major errors in format, references, spelling, and/or grammar make it difficult to understand. |
|
10.0 pts |
| Total Points: 40.0 |
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