Which one of the following is the most likely diagnosis for a 35-year-old female patient with…

Which one of the following is the most likely diagnosis for a 35-year-old female patient with osteosarcoma whose mother was diagnosed with breast cancer at age 30 and who has a brother diagnosed with leukemia at age 22? (A) Li-Fraumeni syndrome (B) BRCA1 and BRCA2 hereditary breast cancer (C) familial adenomatous polyposis (D) neurofibromatosis type 1